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“Inverse modeling unveils governing law of mechano-chemical dynamics of epithelial migration”
Yuto Kikuchi, Yoshifumi Asakura, Kazuhiro Aoki, Yohei Kondo, Honda Naoki
PLOS Computational Biology, 21 (12), e1013854, 2025
DOI: 10.1371/journal.pcbi.1013854 -
“Inverse modeling unveils governing law of mechano-chemical dynamics of epithelial migration”
Yuto Kikuchi, Yoshifumi Asakura, Kazuhiro Aoki, Yohei Kondo, Honda Naoki
PLOS Computational Biology, 21 (12), e1013854, 2025
DOI: 10.1371/journal.pcbi.1013854 -
“A stress granule-associated RNA-binding protein FAM120A drives cisplatin resistance in non-small cell lung cancer”
Shunsaku Hayai, Miho M Suzuki, Kenta Iijima, Keiko Shinjo, Yoshiteru Murofushi, Jingqi Xie, Tatsunori Nishimura, Makoto Ishii, Yutaka Kondo
The Journal of Biochemistry, mvaf074, 2025
DOI: 10.1093/jb/mvaf074 -
“Altered glycolipid metabolism during acute kidney injury exacerbates renal inflammation”
Akinori Osada, Miyako Tanaka, Yuki Sugiura, Xunmei Yuan, Shinji Yamashita, Kozue Ochi, Hiro Kohda, Ayaka Ito, Shiori Go, Tetsuya Okajima, Kenji Kadomatsu, Motoko Yanagita, Kazuhiro Furuhashi, Shoichi Maruyama & Takayoshi Suganami
Scientific Reports, 16, 147, 2025
DOI: 10.1038/s41598-025-28897-4 -
“TFIIH-p52ΔC defines a ninth xeroderma pigmentosum complementation–group XP-J and restores TFIIH stability to p8-defective trichothiodystrophy”
Yuka Nakazawa, Lin Ye, Yasuyoshi Oka, Hironobu Morinaga, Kana Kato, Mayuko Shimada, Kotaro Tsukada, Koyo Tsujikawa, Yosuke Nishio, Hiva Fassihi, Shehla Mohammed, Alan R. Lehmann and Tomoo Ogi
The Journal of Clinical Investigation, 135 (22), e195732, 2025
DOI: 10.1172/JCI195732 -
“Regulation of R-Loop Dynamics by Proteins and Long Noncoding RNAs: An Emerging Paradigm for Cancer Treatment”
Miho M. Suzuki, Keiko Shinjo, Tatsunori Nishimura, Yutaka Kondo
Cancer Science, 0, 1-11, 2025
DOI: 10.1111/cas.70272 -
“Integrative epigenome and transcriptome analyses reveal transcriptional programs differentially regulated by ASCL1 and NEUROD1 in small cell lung cancer”
Hiroshi Takumida, Akira Saito, Yugo Okabe, Yasuhiro Terasaki, Yu Mikami, Hidenori Tanaka, Masami Suzuki, Yu Hamaguchi, Chao Zeng, Michiaki Hamada, Hiroshi I. Suzuki, Hidenori Kage & Masafumi Horie
Oncogene, 44, 3113-3125, 2025
DOI: 10.1038/s41388-025-03481-2 -
“Septin 3 regulates memory and L-LTP-dependent extension of endoplasmic reticulum into spines”
Natsumi Ageta-Ishihara, Yugo Fukazawa, Fumiko Arima-Yoshida, Hiroyuki Okuno, Yuichiro Ishii, Keizo Takao, Kohtarou Konno, Kazuto Fujishima, Hiroshi Ageta, Hiroyuki Hioki, Kunihiro Tsuchida, Yoshikatsu Sato, Mineko Kengaku, Masahiko Watanabe, Ayako M. Watabe, Toshiya Manabe, Tsuyoshi Miyakawa, Kaoru Inokuchi, Haruhiko Bito, Makoto Kinoshita
Cell Reports, 44 (3), 115352, 2025
DOI: 10.1016/j.celrep.2025.115352 -
“Phosphorylated septin 3 delocalizes from the spine base and facilitates endoplasmic reticulum extension into spines via myosin-Va”
Natsumi Ageta-Ishihara, Masato Mizukami, Itsuki Kinoshita, Yurika Asami, Tomoki Nishioka, Haruhiko Bito, Kozo Kaibuchi & Makoto Kinoshita
Molecular Brain, 18, 43, 2025
DOI: 10.1186/s13041-025-01215-9 -
“Novel small molecules disrupting polarized cell expansion and development in the moss, Physcomitrium patens“
Prerna Singh, Naoya Kadofusa, Ayato Sato, Satoshi Naramoto, Tomomichi Fujita
Plant Biotechnology, 42 (2), 131-143, 2025
DOI: 10.5511/plantbiotechnology.25.0209a -
“Biallelic LGI1 and ADAM23 variants cause hippocampal epileptic encephalopathy via the LGI1-ADAM22/23 pathway”
Yoko Hirano, Yuri Miyazaki, Daisuke Ishikawa, Hiroki Inahashi, Zuhair Nasser Al-Hassnan, Giovanni Zifarelli, Peter Bauer, Javeria Raza Alvi, Tipu Sultan, Michelle L Thompson, Abdullah Sezer, Bahadır Konuşkan, Razan S Hajir, Ayman W El-Hattab, Stephanie Efthymiou, Ayuki Ishida, Norihiko Yokoi, Hans-Christian Kornau, Dietmar Schmitz, Harald Prüss, Henry Houlden, Yuji Ikegaya, Yuko Fukata, Masaki Fukata, Reza Maroofian
Brain, 148(10), 3514-3522, 2025
DOI: 10.1093/brain/awaf202 -
“Comprehensive identification of proteins interacting with long non-coding RNA TUG1 in R-loop regulation”
Jingqi Xie, Miho M Suzuki, Kenta Iijima, Keiko Shinjo, Tatsunori Nishimura, Shinya Watanabe, Reiko Nakagawa, Tatsuo Ito, Yutaka Kondo
The Journal of Biochemistry, 178 (4), 251-265, 2025
DOI: 10.1093/jb/mvaf042 -
“Glucose and insulin responses following streptozotocin administration for the induction of a type 1 diabetes mellitus model in Microminipig”
Maria Izumi, Kazuki Hano, Taiki Kato, Akihiro Hirata, Paing Thaw, Azusa Seki, Miyako Tanaka, Kozue Ochi, Takayoshi Suganami, Hitoshi Kitagawa, Masaki Takasu
Journal of Veterinary Medical Science, 87 (10), 1122-1127, 2025
DOI: 10.1292/jvms.25-0145 -
“A Unique Trimeric Assembly of Human Dishevelled 1 PDZ Domain in Crystal: Implication of Homo- and Hetero-Oligomerization During Wnt Signaling Process”
Shotaro Yasukochi, Nobutaka Numoto, Kiminori Hori, Takeshi Tenno, Emi Hibino, Nobutoshi Ito and Hidekazu Hiroaki
Molecules, 30 (17), 3538, 2025
DOI: 10.3390/molecules30173538 -
“Quantification of cyclin-CDK dissociation constants using FCCS with green and near-infrared fluorescent proteins”
Aika Toyama, Yuhei Goto, Yuhei Yamauchi, Hironori Sugiyama, Yohei Kondo, Atsushi Mochizuki, Kazuhiro Aoki
Journal of Cell Science, 138 (17), jcs263921, 2025
DOI: 10.1242/jcs.263921 -
“Integration of Generative Protein Design with Synthetic Porphyrin Assembly: Metal-Responsive Cyclic Assembly of a Bi-Porphyrin Acquisition Designer Protein”
Hiroaki Inaba, Hiroki Onoda, Takayuki Uchihashi, Atsunori Oshima, Osami Shoji
Small, e05625, 2025
DOI: 10.1002/smll.202505625 -
“Characteristic miRNA profiles represent clinicopathological diversity of small cell lung cancer”
Masafumi Horie, Hiroshi Takumida, Hayato Koba, Tsukasa Ueda, Hidenori Tanaka, Masami Suzuki, Yukinobu Ito, Ayumi Ito, Mao Kondo, Hiroshi I Suzuki, Isao Matsumoto, Seiji Yano, Akira Saito, Daichi Maeda
The Journal of Pathology, 267 (2), 168-180, 2025
DOI: 10.1002/path.6458 -
“The protein kinase inhibitor, tyrphostin AG126, and its derivatives suppress phosphorylation of plasma membrane H+-ATPase and light-induced stomatal opening”
Shogo Kuwayama, Maki Hayashi, Koji Takahashi, Yuki Hayashi, Kohei Fukatsu, Kei Murakami, Yusuke Aihara, Ayato Sato, Toshinori Kinoshita
Plant and Cell Physiology, 66(7), 1020-1029, 2025
DOI: 10.1093/pcp/pcaf050 -
“Transcription-coupled repair – mechanisms of action, regulation, and associated human disorders”
Yuka Nakazawa, Yasuyoshi Oka, Tomoko Matsunaga, Tomoo Ogi
FEBS Letters, 599 (2), 166-167, 2025
DOI: 10.1002/1873-3468.15073 -
“Fine Regulation of MicroRNAs in Gene Regulatory Networks and Pathophysiology”
Mayu Seida, Koichi Ogami, Seiko Yoshino and Hiroshi I. Suzuki
International Journal of Molecular Sciences, 26 (7), 2861, 2025
DOI: 10.3390/ijms26072861 -
“Molecular and Biophysical Perspectives on Dormancy Breaking: Lessons from Yeast Spore”
Keiichiro Sakai, Yohei Kondo, Kazuhiro Aoki and Yuhei Goto
Biomolecules, 15 (5), 701, 2025
DOI: 10.3390/biom15050701 -
“Prenatal inflammation impairs early CD11c-positive microglia induction and delays myelination in neurodevelopmental disorders”
Kazuya Fuma, Yukako Iitani, Kenji Imai, Takafumi Ushida, Sho Tano, Kosuke Yoshida, Akira Yokoi, Rika Miki, Hiroyuki Kidokoro, Yoshiaki Sato, Yuichiro Hara, Tomoo Ogi, Kohei Nomaki, Makoto Tsuda, Okiru Komine, Koji Yamanaka, Hiroaki Kajiyama & Tomomi Kotani
Communications Biology, 8, 75, 2025
DOI: 10.1038/s42003-025-07511-3 -
“Novel FBN1 intron variant causes isolated ectopia lentis via in-frame exon skipping”
Norihiro Shimizu, Yoichi Mashimo, Hirotaka Yokouchi, Yosuke Nishio, Setsu Sawai, Tomohiko Ichikawa, Tomoo Ogi, Takayuki Baba & Yoshihiro Onouchi
Journal of Human Genetics, 70, 199-205, 2025
DOI: 10.1038/s10038-025-01318-0 -
“Keratinocyte-driven dermal collagen formation in the axolotl skin”
Ayaka Ohashi, Hirotaka Sakamoto, Junpei Kuroda, Yohei Kondo, Yasuhiro Kamei, Shigenori Nonaka, Saya Furukawa, Sakiya Yamamoto & Akira Satoh
Nature Communications, 16, 1757, 2025
DOI: 10.1038/s41467-025-57055-7 -
“Novel Cell-to-Cell Communications Between Macrophages and Fibroblasts Regulate Obesity-Induced Adipose Tissue Fibrosis”
Hiro Kohda, Miyako Tanaka, Shigeyuki Shichino, Satoko Arakawa, Tadasuke Komori, Ayaka Ito, Eri Wada, Kozue Ochi, Xunmei Yuan, Takehiko Takeda, Atsuhito Saiki, Ichiro Tatsuno, Kenji Ikeda, Yuki Miyai, Atsushi Enomoto, Yoshihiro Morikawa, Shigeomi Shimizu, Satoshi Ueha, Kouji Matsushima, Yoshihiro Ogawa, Takayoshi Suganami
Diabetes, 74 (7), 1135-1152, 2025
DOI: 10.2337/db24-0762 -
“Aversive experiences induce valence plasticity of instructive signals to change future learning rules in mice”
Suguru Tohyama, Takashi Nagashima, Iori Higashino, Fumiko Arima-Yoshida, Kanae Hiyoshi, Masashi Nagase, Yuichiro Yada, Naoki Honda & Ayako M. Watabe
Communications Biology, 8, 1002, 2025
DOI: 10.1038/s42003-025-08367-3 -
“Long-term systemic androgen deprivation partially modulates neuroinflammation in male AppNL-G-F/NL-G-F mice”
Kasumi Maekawa, Akira Sobue, Okiru Komine, Yuko Saito, Shigeo Murayama, Takaomi C. Saido, Takashi Saito & Koji Yamanaka
Scientific Reports, 15, 19666, 2025
DOI: 10.1038/s41598-025-04534-y -
“Non-human primate seasonal transcriptome atlas reveals seasonal changes in physiology and diseases”
Junfeng Chen, Kousuke Okimura, Liang Ren, Yusuke Nakane, Tomoya Nakayama, Yang Chen, Kai Fukawa, Soutarou Sugiyama, Takayoshi Natsume, Naoko Suda-Hashimoto, Mayumi Morimoto, Takako Miyabe-Nishiwaki, Takao Oishi, Yuma Katada, Manhui Zhang, Kohei Kobayashi, Shoko Matsumoto, Taiki Yamaguchi, Ying-Jey Guh, Issey Takahashi, Taeko Nishiwaki-Ohkawa, Daiki X. Sato, Yoshiharu Murata, Kenta Sumiyama, Atsushi J. Nagano, Hiroo Imai & Takashi Yoshimura
Nature Communications, 16, 3906, 2025
DOI: 10.1038/s41467-025-57994-1 -
“Mitochondria and Endoplasmic Reticulum Contact Site as a Regulator of Proteostatic Stress Responses in Neurodegenerative Diseases”
Seiji Watanabe, Koji Yamanaka
BioEssays, 47 (7), e70016, 2025
DOI: 10.1002/bies.70016 -
“Transient Dietary Intervention Induces Healthy AdiposeTissue Expansion and Metabolically Healthy Obesityin Mice”
Eri Wada, Hirotaka Hosono, Miyako Tanaka, Fumi Miyakawa, Kozue Ochi, Hiro Kohda, Shogo Tanno, Reon Shimano, Ayaka Ito, Yasuyuki Kitaura, Kazuya Ichihara, Akinobu Matsumoto, Tomoo Ogi, Noriko Satoh-Asahara, Toyoaki Murohara, Takayoshi Suganami
The FASEB Journal, 39, e70847, 2025
DOI: 10.1096/fj.202501121R -
“Meflin/Islr is a marker of fibroblasts that arise in fibrotic regions after spinal cord injury”
Yoshinori Morita, Yukihiro Shiraki, Akira Kato, Yasuhiro Nagatani, Ryota Ando, Hiroaki Nakashima, Shiro Imagama and Atsushi Enomoto
Nagoya Journal of Medical Science, 87, 305-319, 2025
DOI: 10.18999/nagjms.87.2.305 -
“Structural insights into the engagement of lysophosphatidic acid receptor 1 with different G proteins”
Shota Suzuki, Kotaro Tanaka, Akiko Kamegawa, Kouki Nishikawa, Hiroshi Suzuki, Atsunori Oshima, Yoshinori Fujiyoshi
Journal of Structural Biology, 217, 108164, 2025
DOI: 10.1016/j.jsb.2024.108164 -
“Meflin is a marker of pancreatic stellate cells involved in fibrosis and epithelial regeneration in the pancreas”
Ryota Ando, Yukihiro Shiraki, Yuki Miyai, Hiroki Shimizu, Kazuhiro Furuhashi, Shun Minatoguchi, Katsuhiro Kato, Akira Kato, Tadashi Iida, Yasuyuki Mizutani, Kisuke Ito, Naoya Asai, Shinji Mii, Nobutoshi Esaki, Masahide Takahashi and Atsushi Enomoto
The Journal of Pathology, 262, 61-75, 2024
DOI: 10.1002/path.6211 -
“Distinct microRNA Signature and Suppression of ZFP36L1 Define ASCL1-Positive Lung Adenocarcinoma”
Takayoshi Enokido, Masafumi Horie, Seiko Yoshino, Hiroshi I. Suzuki, Rei Matsuki, Hans Brunnstrom, Patrick Micke, Takahide Nagase, Akira Saito and Naoya Miyashita
Molecular Cancer Research, 22, 29-40, 2024
DOI: 10.1158/1541-7786.MCR-23-0229 -
“ALS-linked mutant TDP-43 in oligodendrocytes induces oligodendrocyte damage and exacerbates motor dysfunction in mice”
Mai Horiuchi, Seiji Watanabe, Okiru Komine, Eiki Takahashi, Kumi Kaneko, Shigeyoshi Itohara, Mayuko Shimada, Tomoo Ogi & Koji Yamanaka
Acta Neuropathologica Communications, 12, 184, 2024
DOI: 10.1186/s40478-024-01893-x -
“Meflin/ISLR is a marker of adipose stem and progenitorcells in mice and humans that suppresses white adiposetissue remodeling and fibrosis”
Toshikazu Ishihara, Katsuhiro Kato, Kotaro Matsumoto, Miyako Tanaka, Akitoshi Hara, Yukihiro Shiraki, Hidenori Morisaki, Yuya Urano, Ryota Ando, Kisuke Ito, Shinji Mii, Nobutoshi Esaki, Kazuhiro Furuhashi, Mikito Takefuji, Takayoshi Suganami, Toyoaki Murohara, Atsushi Enomoto
Genes to Cells, 29(10), 902-920, 2024
DOI: 10.1111/gtc.13154 -
“Lipid metabolism in myeloid cell function and chronic inflammatory diseases”
Ayaka Ito and Takayoshi Suganami
Frontiers in Immunology, 15, 1495853, 2024
DOI: 10.3389/fimmu.2024.1495853 -
“Imeglimin Exhibits Novel Anti-Inflammatory Effects on High-Glucose-Stimulated Mouse Microglia through ULK1-Mediated Suppression of the TXNIP–NLRP3 Axis”
Hisashi Kato, Kaori Iwashita, Masayo Iwasa, Sayaka Kato, Hajime Yamakage, Takayoshi Suganami, Masashi Tanaka and Noriko Satoh-Asahara
Cells, 13(3), 284, 2024
DOI: 10.3390/cells13030284 -
“Novel insights into brain lipid metabolism in Alzheimer’s disease: Oligodendrocytes and white matter abnormalities”
Noe Kawade and Koji Yamanaka
FEBS Open Bio, 14(2), 194-216, 2024
DOI: 10.1002/2211-5463.13661 -
“Genetic background variation impacts microglial heterogeneity and disease progression in amyotrophic lateral sclerosis model mice”
Okiru Komine, Syuhei Ohnuma, Kunihiko Hinohara, Yuichiro Hara, Mayuko Shimada, Tomohiro Akashi, Seiji Watanabe, Akira Sobue, Noe Kawade, Tomoo Ogi, and Koji Yamanaka
iScience, 27(2), 108872, 2024
DOI: 10.1016/j.isci.2024.108872 -
“Phase-separated super-enhancers confer an innate radioresistance on genomic DNA”
Koki Matsumoto, Dini Kurnia Ikliptikawati, Kei Makiyama, Kako Mochizuki, Maho Tobita, Isao Kobayashi, Dominic Chih-Cheng Voon, Keesiang Lim, Kazuma Ogawa, Ikuo Kashiwakura, Hiroshi I Suzuki, Hironori Yoshino, Richard W Wong, Masaharu Hazawa
Journal of Radiation Research, 65(4), 482-490, 2024
DOI: 10.1093/jrr/rrae044 -
“A hyperpolarizing neuron recruits undocked innexin hemichannels to transmit neural information in Caenorhabditis elegans“
Airi Nakayama, Masakatsu Watanabe, Riku Yamashiro, Hiroo Kuroyanagi, Hironori J. Matsuyama, Atsunori Oshimad, Ikue Mori,and Shunji Nakano
PNAS, 121(21), e2406565121, 2024
DOI: 10.1073/pnas.2406565121 -
“A class of chemical compounds enhances clustering of muscle nicotinic acetylcholine receptor in cultured myogenic cells”
Yuichi Miyairi, Bisei Ohkawara, Ayato Sato, Ryusuke Sawada, Hisao Ishii, Hiroyuki Tomita, Taro Inoue, Hiroaki Nakashima, Mikako Ito, Akio Masuda, Yasuyuki Hosono, Shiro Imagama, Kinji Ohno
Biochemical and Biophysical Research Communications, 731, 150400, 2024
DOI: 10.1016/j.bbrc.2024.150400 -
“Synthesis and preclinical testing of a selective beta-subtype agonist of thyroid hormone receptor ZTA-261”
Masakazu Nambo, Taeko Nishiwaki-Ohkawa, Akihiro Ito, Zachary T. Ariki, Yuka Ito, Yuuki Kato, Muhammad Yar, Jacky C. -H. Yim, Emily Kim, Elizabeth Sharkey, Keiko Kano, Emi Mishiro-Sato, Kosuke Okimura, Michiyo Maruyama, Wataru Ota, Yuko Furukawa, Tomoya Nakayama, Misato Kobayashi, Fumihiko Horio, Ayato Sato, Cathleen M. Crudden & Takashi Yoshimura
Communications Medicine, 4, 152, 2024
DOI: 10.1038/s43856-024-00574-z -
“Exclusive expression of KANK4 promotes myofibroblast mobility in keloid tissues”
Mayumi Oishi, Keiko Shinjo, Keisuke Takanari, Ayako Muraoka, Miho M. Suzuki, Miki Kanbe, Shinichi Higuchi, Katsumi Ebisawa, Kazunobu Hashikawa, Yuzuru Kamei & Yutaka Kondo
Scientific Reports, 14, 8725, 2024
DOI: 10.1038/s41598-024-59293-z -
“Endogenous aldehyde-induced DNA-protein crosslinks are resolved by transcription-coupled repair”
Yasuyoshi Oka, Yuka Nakazawa, Mayuko Shimada & Tomoo Ogi
Nature Cell Biology, 26(5), 784-796, 2024
DOI: 10.1038/s41556-024-01401-2 -
“Synthetic retinoid-mediated preconditioning of cancer-associated fibroblasts and macrophages improves cancer response to immune checkpoint blockade”
Takayuki Owaki, Tadashi Iida, Yuki Miyai, Katsuhiro Kato, Tetsunari Hase, Makoto Ishii, Ryota Ando, Kunihiko Hinohara, Tomohiro Akashi, Yasuyuki Mizutani, Takuya Ishikawa, Shinji Mii, Yukihiro Shiraki, Nobutoshi Esaki, Masami Yamamoto, Tetsuya Tsukamoto, Sachiyo Nomura Takashi Murakami, Masahide Takahashi, Yuri Yuguchi, Motohiro Maeda, Tomoyasu Sano, Naoto Sassa, Yoshihisa Matsukawa, Hiroki Kawashima, Shusuke Akamatsu and Atsushi Enomoto
British Journal of Cancer, 131, 372-386, 2024
DOI: 10.1038/s41416-024-02734-3 -
“The role of circadian clock gene Arntl in the winter depression-like behavior in melatonin-proficient female CBA/N mice”
Liang Ren, Kousuke Okimura, Akira Ishikawa, Naohiro Kon, Shigeki Shimba, Takashi Yoshimura
Biochemical and Biophysical Research Communications, 734, 150790, 2024
DOI: 10.1016/j.bbrc.2024.150790 -
“Age-related ciliopathy: Obesogenic shortening of melanocortin-4 receptor-bearing neuronal primary cilia”
Manami Oya, Yoshiki Miyasaka, Yoshiko Nakamura, Miyako Tanaka, Takayoshi Suganami, Tomoji Mashimo, Kazuhiro Nakamura
Cell Metabolism, 36(5), 1044-1058, 2024
DOI: 10.1016/j.cmet.2024.02.010 -
“Novel pharmacologic inhibition of lysine-specific demethylase 1 as a potential therapeutic for glioblastoma”
Keiko Shinjo, Takashi Umehara, Hideaki Niwa, Shin Sato, Keisuke Katsushima, Shinya Sato, Xingxing Wang, Yoshiteru Murofushi, Miho M. Suzuki, Hiroo Koyama & Yutaka Kondo
Cancer Gene Therapy, 31, 1884-1894, 2024
DOI: 10.1038/s41417-024-00847-8 -
“Microglial cannabinoid receptor type II stimulation improves cognitive impairment and neuroinflammation in Alzheimer’s disease mice by controlling astrocyte activation”
Akira Sobue, Okiru Komine, Fumito Endo, Chihiro Kakimi, Yuka Miyoshi, Noe Kawade, Seiji Watanabe, Yuko Saito, Shigeo Murayama, Takaomi C. Saido, Takashi Saito & Koji Yamanaka
Cell Death & Disease, 15, 858, 2024
DOI: 10.1038/s41419-024-07249-6 -
“Long noncoding RNA TUG1 promotes cisplatin resistance in ovarian cancer via upregulation of DNA polymerase eta”
Ryosuke Sonobe, Peng Yang, Miho M. Suzuki, Keiko Shinjo, Kenta Iijima, Nobuhiro Nishiyama, Kanjiro Miyata, Kazunori Kataoka, Hiroaki Kajiyama, Yutaka Kondo
Cancer Science, 115, 1910-1923, 2024
DOI: 10.1111/cas.16150 -
“Clinical utility of BRCA and ATM mutation status in circulating tumour DNA for treatment selection in advanced pancreatic cancer”
Kentaro Sudo, Yoshiaki Nakamura Naohiro Okano, Makoto Ueno, Masayuki Furukawa, Nobumasa Mizuno, Yasuyuki Kawamoto, Kumiko Umemoto, Akinori Asagi, Masato Ozaka, Koushiro Ohtsubo, Satoshi Shimizu, Nobuhisa Matsuhashi, Shinji Itoh, Toshihiko Matsumoto, Taroh Satoh, Hiroyuki Okuyama, Masahiro Goto, Hiroko Hasegawa, Yoshiyuki Yamamoto, Justin I. Odegaard, Hideaki Bando, Takayuki Yoshino, Masafumi Ikeda Chigusa Morizane
British Journal of Cancer, 131, 1237-1245, 2024
DOI: 10.1038/s41416-024-02834-0 -
“Dimethyl fumarate improves cognitive impairment and neuroinflammation in mice with Alzheimer’s disease”
Ting Wang, Akira Sobue, Seiji Watanabe, Okiru Komine, Takaomi C. Saido, Takashi Saito & Koji Yamanaka
Journal of Neuroinflammation, 21, 55, 2024
DOI: 10.1186/s12974-024-03046-2 -
“Ebselen analogues delay disease onset and its course in fALS by on-target SOD-1 engagement”
Seiji Watanabe, Kangsa Amporndanai, Raheela Awais, Caroline Latham, Muhammad Awais, Paul M. O’Neill, Koji Yamanaka & S. Samar Hasnain
Scientific Reports, 14, 12118, 2024
DOI: 10.1038/s41598-024-62903-5